Thrombocytopenia risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-In-Chief: Farbod Zahedi Tajrishi, M.D. [2]


High risk patients for thrombocytopenia include: Have certain types of cancer, aplastic anemia, or autoimmune diseases, are exposed to certain toxic chemicals, have a reaction to certain medicines, have certain viruses, and have certain genetic conditions.

Risk Factors

People who are at highest risk for thrombocytopenia are those affected by one of the conditions or factors discussed in the "Causes" section. This includes people who:

  • Have certain types of cancer, aplastic anemia, or autoimmune diseases
  • Are exposed to certain toxic chemicals
  • Have a reaction to certain medicines
  • Have certain viruses
  • Have certain genetic conditions

People at highest risk also include heavy alcohol drinkers and pregnant women.[1]

Non-alcoholic fatty liver disease, especially if with cirrhosis, may be associated with thrombocytopenia[2][3].


  1. [ "Thrombocytopenia | National Heart, Lung, and Blood Institute (NHLBI)".]"Thrombocytopenia | National Heart, Lung, and Blood Institute (NHLBI)". 
  2. Rivera-Álvarez M, Córdova-Ramírez AC, Elías-De-La-Cruz GD, Murrieta-Álvarez I, León-Peña AA, Cantero-Fortiz Y; et al. (2021). "Non-alcoholic fatty liver disease and thrombocytopenia IV: its association with granulocytopenia". Hematol Transfus Cell Ther. doi:10.1016/j.htct.2021.06.004. PMID 34312112 Check |pmid= value (help).
  3. Panke CL, Tovo CV, Villela-Nogueira CA, Cravo CM, Ferreira FC, Rezende GFM; et al. (2020). "Evaluation of thrombocytopenia in patients with non-alcoholic fatty liver disease without cirrhosis". Ann Hepatol. 19 (1): 88–91. doi:10.1016/j.aohep.2019.05.011. PMID 31575467.

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