Torsades de pointes causes

	Torsades de pointes Microchapters
Home
Patient Information
Overview
Historical Perspective
Pathophysiology
Causes
Differentiating Torsades de pointes from other Diseases
Risk Factors
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
EKG Examples
Echocardiography
Other Diagnostic Studies
Treatment
Medical Therapy
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Torsades de pointes causes On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Torsades de pointes causes All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Torsades de pointes causes
CDC on Torsades de pointes causes
Torsades de pointes causes in the news
Blogs on Torsades de pointes causes
Directions to Hospitals Treating Torsades de pointes
Risk calculators and risk factors for Torsades de pointes causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Common causes for torsades de pointes include hypomagnesemia and hypokalemia. It is commonly seen in malnourished individuals and chronic alcoholics. Drug interactions such as erythromycin or Avelox, taken concomitantly with inhibitors like nitroimidazole, diarrhea, dietary supplements, and various medications like methadone, lithium, tricyclic antidepressants or phenothiazines may also contribute to causing torsades de pointes.

Causes

The List of Drugs that Cause Torsades de pointes

Drugs that are generally accepted to have a risk of causing torsades de pointes:

Drugs that Possibly Cause Torsades de pointes

Drugs that in some reports have been associated with torsades de pointes and/or QT prolongation but at this time lack substantial evidence for causing torsades de pointes.

The List of Drugs that Cause Torsades de pointes in Certain Conditions

Drugs that, in some reports, have been weakly associated with torsades de pointes and/or QT prolongation but that are unlikely to be a risk for torsades de pointes when used in usual recommended dosages and in patients without other risk factors (e.g., concomitant QT prolonging drugs, bradycardia, electrolyte disturbances, congenital long QT syndrome, concomitant drugs that inhibit metabolism)

Sources

http://www.qtdrugs.org/

References